Your one best shot is the first one, before the body begins to reproduce the defective cells or antibodies, because once the body begins to reproduce them, it will recognize the reproductions as self and no longer attempt to destroy them. At this point, the best we can hope for is to create a modulating effect on the immune function slowing or stopping the forward progression of the problem, thereby allowing the body to focus more on healing and repair as opposed to being under constant siege. This has quite often proceeded to the point that the patient became totally symptom-free, at which time they went to a maintenance dose to help keep it in check. This is one of the strongest reasons why we would want to continue on the preventive/maintenance dose once we have improved our current health condition.

Ed Callaway R.Ph. has worked for over 30 years as a Pharmacist with a major focus on the interrelationship of dietary supplements, stress management, the immune system, and this overall relationship to healing rates. His training and experiences with patients while counseling them as a Pharmacist since 1970, led him to focus on the relationship of stress on immune system function. As the Pharmacist heading up global distribution of supplements, he was able to interview patients on a large scale getting before and after use reports from them. Universal Response to Major Stress Factors: He found a virtually unanimous answer to the following question to be the same the world over: What major traumatic event happened in your life 6 to 9 months prior to the onset of original symptoms? Virtually all had an answer ranging from: Mom died 6 months prior to the onset of MS symptoms, had a baby with low finances, a bad work environment, a bad personal relationship, etc. He recalled one that said her brother was in an auto accident and placed in intensive care. Two months later her bloodwork showed the first indicators of an autoimmune disease. She learned of the possible connection in one of his meetings. One of the suggested mechanisms of stress effects on the immune system is that normally the body prepares an antibody to attack an incoming virus, but simply makes a mistake. This defective antibody would have normally been destroyed by a fully functional and healthy immune system, which would have recognized it as non-self and destroyed it. However, improperly managed stress of a major magnitude can divert immune system focus allowing the defective antibody to begin reproducing itself. Once this happens, the immune system will no longer attempt to destroy it since it recognizes the reproductions to be self. At this point, the best we can hope for is to create a modulating effect on the immune function slowing or stopping the forward progression of the problem allowing the body to focus more on healing and repair as opposed to being under constant siege. This has quite often proceeded to the point that the patient became totally symptom-free, at which time they went to a maintenance dose to help keep it in check. The thymus may actually reduce in size by as much as 50% in response to a major stressful event. This diversion of T-Cells away from their normal function, in search of the nebulous stress that they will never find, lowers the efficiency of the immune function. What we are attempting to do with Thymate™, an immune system formulation, is to help the immune system be all it can be.

A doctor in Savannah, GA stuck his finger while operating on an infected patient in 1983, contracted hepatitis B, and became a carrier. Several years later and still a carrier, he realized that there had to be a reason for his continued inability to get well. He recalled from medical school that the thymus gland controls the immune system. The gland is large in children and decreases in size as we grow older. He went to a health food store and bought a thymic formula and a vitamin/mineral complex supplement containing B complex, vitamins E and C, selenium, zinc, beta-carotene, and an amino acid complex. After taking these supplements for six weeks, he no longer was a hepatitis carrier. He notified the Center for Disease Control in Atlanta, Georgia. They took blood samples and sent them to Massachusetts General at Harvard and to Scripps Institute in California. Many studies were completed, including PCRs, DNA, etc., all having negative test results for the hepatitis virus.

After testing the supplements in his laboratory, Dr. Milton G. Mutchnick, a gastroenterologist/hepatologist researcher at Wayne State University in Detroit stated that the products had a tremendous stimulating effect on the immune system. Dr. Mutchnick took the supplements himself and measured his blood levels of thymosin Alpha 1. He stated "You might be pleased to know that I did a pilot study on myself by taking several of the thymic formula and vitamin/mineral tablets. I first obtained a pretreatment serum sample followed by samples taken at 1/2 hour and then at 1 hour intervals, for 4 hours.

Lo and behold, by the first hour and consistently for the next several hours, the thymosin Alpha 1 levels, as determined by the ELISA test, increased." Dr. Mutchnick felt that it would be necessary to repeat this study with a number of subjects; but he could see the exciting potential of this product for stimulating the immune system.

Melvin L. Haysman, M.D., who practices allergy and clinical immunology in Savannah, Georgia, used the supplements. Dr. Haysman gathered before and after serum samples on a dozen patients who took the supplements and sent them to Dr. Mutchnick. He found that 100 percent of the test patients had increases in the thymosin Alpha 1 levels. The increases ranged from 300 to 700 percent depending on the dosage of the supplements. Dr. Mutchnick also found that the thymic/glandular complex supplement was inactive without the vitamin/mineral complex serving as an activating agent.

The vitamin/mineral complex supplement activates the thymic/glandular complex supplement, because the vitamins and minerals are coenzymes which activate the enzyme system and prepare the substrate. The thymic complex then stimulates the immune system to produce interferon, interleukin, RBCs, WBCs, T cells, etc.

Other exciting progress with the use of the herbal/glandular/vitamin/mineral complex supplements(thymic complex) involves three transplant patients. These individuals were scheduled to have liver transplants and are now no longer on transplant lists having recovered from their chronic hepatitis. Other cases involved two liver transplant patients and one heart transplant patient, all who contracted hepatitis B during blood transfusions. These three patients were told that their bodies were rejecting their organs and that there was no treatment for their hepatitis. After using the herbal/glandular/vitamin/mineral complex(thymic complex), they have become non-carrier hepatitis B patients and have also retained their new organs. The thymic complex appears to have a modulating effect bringing hyperactive conditions such as rheumatoid arthritis down and hypo-immune conditions, such as cancer, up. The success of using these products could have an enormous impact on organ transplant operations. Current medicines being used for

organ transplant patients destroy the immune system and confine the patients to their homes. The thymic/glandular complex combined with the vitamin/mineral complex may enable organ transplant patients to lead normal lives by improving their immune system.

This is not an alternative form of medicine.
Within the medical community, any gland that decreases in size or "dries up" in your body is replaced. If your thyroid dries up, we give you thyroid; if your pancreas dries up (you get diabetes), we give you insulin; if your adrenal glands dry up (you get Addison's Disease), we give you cortisone; and if your ovaries dry up, we give you female hormones. However, when the thymus gland dries up, no one treats that as a medical condition even though every health professional is taught that the thymus gland controls the immune system. Your thymus gland begins to dry up between puberty and twenty, and by age fifty, it is about gone; yet it is central in controlling the immune system function. The older we get and/or the greater the stress we encounter, the more allergies we run into that our immune system is unable to process and the more immune and/or autoimmune disorders we accumulate. This is why proper stress management and nutritional supplementation is of utmost importance in our focus on healing and disease prevention.

The thymus gland controls the immune system in two ways. First, it is the source of

T (thymus) cells or T lymphocytes. It is these T cells that fight the battle against viruses, bacteria, yeast, and other foreign invaders that attack the body's immune system. The thymus gland seeds the bone marrow with immature T cells that multiply and mature. (Once it strikes home that the "T" in T cells stands for "thymus", we begin to wake up to the value of thymus supplements with full nutritional support as is in Thymate™.)

Second, the thymus gland produces a variety of hormones that stimulate the maturation of T cells and increase production of other hormones, such as interferon and the immune globulins. Several hormones have been isolated from the thymus, but the one receiving the most attention in medical studies right now is thymosin Alpha 1.

For example, it is the T cell that is destroyed by the HIV virus and its destruction brings on AIDS. Animal studies have been done in Texas that have resulted in the HIV virus being arrested after using the thymic supplement. It stands to reason that an HIV patient taking this supplement should never convert to an AIDS patient because the thymus produces the T cells to prevent the conversion as well as producing interleukin 2 to slow down the conversion. Similar viruses have responded well to the use of the supplement, as well as herpes and condyloma acuminata without any recurrence for as long as 27 months.

In 1991, a physician at the University of Miami Medical School said that they had just finished an eight-year multi-center study which showed that the actual laying down of the atherosclerotic plaque within the blood vessel walls occurs as the result of the

failure of the immune system. When do you see significant atherosclerotic changes in human beings? It is around the age of twenty, when the thymus gland decreases in size. Thymus supplementation may prevent atherosclerotic disease; studies need to be done.

A group of researchers at the University of California in Los Angeles had been doing longevity studies and had found that life extension boils down to the ability of a cell to regenerate itself. Cell regeneration depends entirely upon an intact immune system. These researchers had rats that lived an additional two generations taking thymic supplements. The implication, of course, is that maintaining a strong immune system can help you in many ways, such as fighting diseases, bacteria, viruses, and yeast-related disorders.

Callaway states, "The philosophy of my pharmacy practice has always been that if you maintain normal physiology and utilize good stress management, you can prevent disease and pathology." This includes the supplementation of glands that have reduced in size or have been damaged by disease or other foreign invaders. This also includes using the best possible dietary supplements to assure a proper balance of nutrients enabling the body to better heal and defend itself.

NEW DEVELOPMENTS: In May 1997, Callaway founded ThyMates, Inc. pro-ducing Thymate™ and implemented major changes based on feedback from health professionals on a global basis. The major changes in Thymate™ consists of the use of natural pharmaceutical grade glandulars, a major focus on natural ingredients, and a truly natural clear pharmaceutical glaze as a coating. Thymate™ differs from products using edible grade glandulars. Edible grade simply means: "suitable as food for mankind." Examples of the differences between natural pharmaceutical and edible grade glandulars is that the natural pharmaceutical grade glandulars in Thymate™ must meet higher standards of purity by being free of growth hormones, antibiotics, and chemical residues. Thymate™ has been designed and prepared to my specifications utilizing the latest pharmaceutical techniques along with the highest quality natural ingredients. It is easy to swallow and dissolves quickly for ready absorption. Thymate™ even has a pleasant smell and aftertaste.

All ingredients are natural and there are no known side effects. This dietary substance does not interfere with other medications.

This information is for educational purposes only and is not meant to diagnose, treat, cure, or prevent any disease or disorder or to replace professional medical advice. Please consult your physician when using this and other food supplements. This literature may be reproduced without legal ramifications.